Non-linear optimization of biochemical pathways: applications to metabolic engineering and parameter estimation
نویسندگان
چکیده
منابع مشابه
Non-linear optimization of biochemical pathways: applications to metabolic engineering and parameter estimation
MOTIVATION The simulation of biochemical kinetic systems is a powerful approach that can be used for: (i) checking the consistency of a postulated model with a set of experimental measurements, (ii) answering 'what if?' questions and (iii) exploring possible behaviours of a model. Here we describe a generic approach to combine numerical optimization methods with biochemical kinetic simulations,...
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ژورنال
عنوان ژورنال: Bioinformatics
سال: 1998
ISSN: 1367-4803,1460-2059
DOI: 10.1093/bioinformatics/14.10.869